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Renal Cell Carcinoma

Investigators at Masaryk Memorial Cancer Institute zero in on renal cell carcinoma

Published in Cancer Weekly, August 10th, 2010

Research findings, 'Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy,' are discussed in a new report. "MicroRNAs are endogenously expressed regulatory noncoding RNAs. Previous studies have shown altered expression levels of several microRNAs in renal cell carcinoma," researchers in Brno, Czech Republic report.

"We examined the expression levels of selected microRNAs in 38 samples of conventional renal cell carcinoma (RCC) and 10 samples of non-tumoral renal parenchyma using TaqMan real-time PCR method. The expression levels of miRNA-155 (p <0.0001), miRNA-210 (p <0.0001),...

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