Cancer
Findings from Health Protection Agency in cancer reported
Published in Cancer Weekly, October 12th, 2010
A report, 'Xrcc2 modulates spontaneous and radiation-induced tumorigenesis in Apcmin/+ mice,' is newly published data in Molecular Cancer Research. According to a study from Chilton, the United Kingdom, "XRCC2 has an important role in repair of DNA damage by homologous recombination. Adult Apc(min/+) (min, multiple intestinal neoplasia) mice, wild-type or heterozygous for Xrcc2 deficiency, were sham-irradiated or 2-Gy X-irradiated."
"Spontaneous mammary and intestinal tumor incidences are lower in Apc(min/+) Xrcc2(±) mice than in Apc(min/+) Xrcc2(+/+) mice (mammary tumors: 14% and 38%, respectively, '(2) p=0.03; intestinal adenomas in mice reaching full...
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Source: Cancer Weekly (2010-10-12)
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