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Breast Cancer

Studies from G.C. Barnett et al add new findings in the area of breast cancer

Published in Cancer Weekly, January 11th, 2011

2011 JAN 11 -- "Several small studies have reported associations between TGFB1 single nucleotide polymorphisms (SNPs), considered to increase secretion of TGF-beta 1, and greater than 3-fold increases in incidence of fibrosis - an indicator of late toxicity after radiotherapy in breast cancer patients. Two SNPs in TGFB1, C-509T (rs1800469) and L10P (rs1800470), were genotyped in 778 breast cancer patients who had received radiotherapy to the breast," scientists writing in the journal Radiotherapy and Oncology report.

"Late radiotherapy toxicity was assessed two years after radiotherapy using a validated photographic technique, clinical assessment and...

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