Lung Cancer

New Lung Cancer Findings from University of Toronto Described

Published in Cancer Weekly, February 1st, 2011

2011 FEB 1 -- According to recent research from Toronto, Canada, "Alternative splicing (AS) is a widespread mechanism underlying the generation of proteomic and regulatory complexity. However, which of the myriad of human AS events play important roles in disease is largely unknown."

"To identify frequently occurring AS events in lung cancer, we used AS microarray profiling and reverse transcription-PCR (RT-PCR) assays to survey patient-matched normal and adenocarcinoma tumor tissues from the lungs of 29 individuals diagnosed with non-small cell lung cancer (NSCLC). Of 5,183 profiled alternative exons, four displayed tumor-associated changes in the majority...

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Source: Cancer Weekly (2011-02-01)

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