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Carcinomas

Research from University of Heidelberg, Institute of Pathology Provides New Data on Carcinomas

Published in Cancer Weekly, February 15th, 2011

2011 FEB 15 -- Scientists discuss in 'Expression and prognostic relevance of the death receptor CD95 (Fas/APO1) in renal cell carcinomas' new findings in Carcinomas. "CD95 (Fas/APO1) is one of the best known members of the death receptor family which can either mediate apoptosis or activate tumor-promoting pathways. Using a tissue microarray we investigated the association between the expression of CD95 and prognosis in 617 patients with renal cell carcinomas (RCCs)," investigators in Germany report.

"CD95 was expressed in the vast majority of RCCs. High CD95 expression was associated with lymph node metastasis and correlated negatively with...

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