Lung Cancer
Findings from Soochow University, Medical College in Lung Cancer Reported
Published in Cancer Weekly, March 1st, 2011
2011 MAR 1 -- Investigators publish new data in the report 'A haplotype of TGFBR1 is predominantly found in non-small cell lung cancer patients displaying TGFBR1 allelic-specific expression.' According to a study from Suzhou, People's Republic of China, "Non-small cell lung cancer (NSCLC) accounts for ~85% of all cases of lung cancer and TGF-ß refractoriness is very common in NSCLC cells. Constitutively decreased TGFBR1 expression, probably leading to TGF-ß resistance in tumors, is emerging as a novel tumor-predisposing phenotype."
"However, the precise genetic/epigenetic mechanisms underlying the role of TGFBR1 in NSCLC carcinogenesis are still...
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Source: Cancer Weekly (2011-03-01)
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