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Pharmaceutical and Research

Research on Pharmaceutical and Research Reported by Scientists at Northeastern University

Published in Cancer Weekly, March 8th, 2011

2011 MAR 8 -- According to recent research published in the journal Pharmaceutical Research, "To evaluate the potential of palmitoyl ascorbate (PA)-loaded micelles for ascorbate-mediated cancer cell targeting and cytotoxicity. PA was incorporated in polyethylene glycol-phosphatidyl ethanolamine micelles at varying concentrations."

"The formulations were evaluated for PA content by RP-HPLC. A stable formulation was selected based on size and zeta potential measurements. A co-culture of cancer cells and GFP-expressing non-cancer cells was used to determine the specificity of PA micelle binding. In vitro cytotoxicity of the micellar formulations towards...

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