Leukemia

Data on Leukemia Described by M.L. Demesquita et al

Published in Cancer Weekly, March 15th, 2011

2011 MAR 15 -- "In the search for new anti-cancer compounds, Brazilian Cerrado plant species have been investigated. The hexane root bark extract of Kielmeyera coriacea lead to a mixture of delta-tocotrienol (1) and its dimer (2)," scientists in Brasilia, Brazil report.

"The structures of both compounds 1 and 2 were established based on detailed 1D and 2D NMR and EI-MS analyses. The cytotoxicity of the mixture was tested against four human tumor cell lines in the following cultures: MDA-MB-435 (melanoma), HCT-8 (colon), HL-60 (leukemia), and SF-295 (glioblastoma), and displayed IC50 values ranging from 8.08 to 23.58 mu g/mL. Additional assays were performed...

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Source: Cancer Weekly (2011-03-15)

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