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European Molecular Biology Laboratory

Suggesting genes' friends, Facebook-style

Published in Cancer Weekly, March 22nd, 2011

2011 MAR 22 -- Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can amplify, cancel out or mask each others' effects, and enables scientists to suggest genes that interfere with each other in much the same manner that facebook suggests friends.

To understand the connections between genetic make-up and traits like disease susceptibility, scientists have been turning to genome-wide association studies, in which they...

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