Genetics and Breast Cancer

Scientists identify KRAS rearrangements in metastatic prostate cancer

Published in Cancer Weekly, April 19th, 2011

2011 APR 19 -- ORLANDO, Fla. - Scientists have uncovered a genetic characteristic of metastatic prostate cancer that defines a rare sub-type of this disease. These findings are published in Cancer Discovery, the newest journal of the American Association for Cancer Research, which will debut at the AACR 102nd Annual Meeting 2011, held April 2-6.

Arul M. Chinnaiyan, M.D., Ph.D., an investigator of the Howard Hughes Medical Institute and director of the Michigan Center for Translational Pathology, and colleagues identified an oncogenic gene fusion of KRAS, one of the most studied and well-known oncogenes in a metastatic prostate cancer cell line.

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Source: Cancer Weekly (2011-04-19)

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