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Bladder Cancer

Studies in the Area of Bladder Cancer Reported from L.A. Kiemeney and Co-Researchers

Published in Cancer Weekly, May 17th, 2011

2011 MAY 17 -- New research, 'A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer,' is the subject of a report. According to a study from Nijmegen, Netherlands, "Previously, we reported germline DNA variants associated with risk of urinary bladder cancer (UBC) in Dutch and Icelandic subjects. Here we expanded the Icelandic sample set and tested the top 20 markers from the combined analysis in several European case-control sample sets, with a total of 4,739 cases and 45,549 controls."

"The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio=1.24, p=9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70...

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