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Carcinogenesis

Panjab University Describes Research in Carcinogenesis

Published in Cancer Weekly, May 24th, 2011

2011 MAY 24 -- Current study results from the report, "Azadirachta indica exerts chemopreventive action against murine skin cancer: studies on histopathological, ultrastructural changes and modulation of NF-kappaB, AP-1, and STAT1," have been published. According to recent research from Chandigarh, India, "The present study reports the histopathological, ultrastructural changes and modulation of NF-kappaB, AP-1, and STAT 1 during skin carcinogenesis in LACA mice and its intervention with Azadirachta indica. Skin tumors were induced by topical application of 7,12-dimethylbenz(a)anthracene (DMBA) (500 nmol/100 microl for 2 weeks) followed by 12-O-tetradecanoylphorbol-13-acetate...

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