Colon Cancer
Study Findings from Mayo Clinic College of Medicine Broaden Understanding of Colon Cancer
Published in Cancer Weekly, May 31st, 2011
2011 MAY 31 -- New investigation results, "Chromosome missegregation causes colon cancer by APC loss of heterozygosity," are detailed in a study published in Cell Cycle. "A longstanding hypothesis in the field of cancer biology is that aneuploidy causes cancer by promoting loss of chromosomes that contain tumor suppressor genes. By crossing aneuploidyprone Bub1 hypomorphic mice onto a heterozygous null background for p53, we provided conclusive evidence for this idea.(1) Surprisingly, the tumors that developed in this model had not just lost the chromosome 11 copy harboring wild-type p53, but had also gained an extra copy of chromosome 11 bearing the p53 null allele,"...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2011-05-31)
More Articles from Cancer Weekly
- Children's Hospital Boston
Children's Hospital Boston Ranked #1 by U.S. News & World Report in More Specialties Than Any Other Children's Hospital in the Nation - Colon Cancer
Data on Colon Cancer Published by D. Hock and Colleagues - Colon Cancer
Data on Colon Cancer Reported by H. Nishida and Co-Researchers - Elekta
Elekta Acknowledges Cancer Registrars' Contribution to Human Care at NCRA Education Conference - Lung Cancer
End of life care for cancer patients differs in US and Canada - Prostate Cancer
Experts Discuss Emerging Treatments and Multi-Disciplinary Approaches to Prostate Cancer Care - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
