Stem Cell Research

Study Data from Chiba University Provide New Insights into Stem Cell Research

Published in Cancer Weekly, June 7th, 2011

2011 JUN 7 -- Current study results from the report, "Approaches to neural stem cells and cancer cells based on natural products," have been published. According to a study from Chiba, Japan, "We have developed 'protein-and cell-based screen methods' for the isolation of new natural products. By using VDR (vitamin D receptor) immobilized magnetic beads, two new natural products were isolated rapidly."

"To find inhibitors of Hes1 protein, which is one of the important transcriptional factors in neural stem cells, a Hes1 dimer plate assay was developed, and then first Hes1 dimer inhibitors were found from our natural products library. As a 'cell-based screen...

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Source: Cancer Weekly (2011-06-07)

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