2011 JUN 7 -- Data detailed in "CD4+ T cells elicit host immune responses to MHC class II-negative ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells" have been presented. "T cell adoptive transfer strategies that have produced clinical remissions against specific tumors have so far produced disappointing results against ovariancancer. Recent evidence suggests that adoptively transferred CD4(+) T cells can trigger endogenous immune responses in particular patients with ovarian cancer through unknown mechanisms," investigators in Lebanon, United States report.
"However, conflicting reports suggest that ovarian...
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