Apoptosis
Findings in Apoptosis Reported from Zhengzhou University
Published in Cancer Weekly, June 21st, 2011
2011 JUN 21 -- Fresh data on Apoptosis are presented in the report "Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1." According to recent research from Zhengzhou, People's Republic of China, "Resveratrol is a natural polyphenolic compound with cancer chemopreventive activity. However, our understanding of the molecular mechanism responsible for resveratrol-induced apoptosis is still very limited."
"Here, we used MCF-7 and MDA-MB231 breast cancer cells as a model to demonstrate that resveratrol induced the expression of ASPP1, a new member of the ASPP (apoptosis stimulation protein of p53) family, which plays an...
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Source: Cancer Weekly (2011-06-21)
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