Colon Cancer
Research Conducted at Institute for Cancer Research Has Updated Our Knowledge about Colon Cancer
Published in Cancer Weekly, July 26th, 2011
2011 JUL 26 -- Scientists discuss in "DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer" new findings in Colon Cancer. "Gap junctions are specialized plasma membrane domains consisting of channels formed by members of the connexin protein family. Gap junctional intercellular communication is often lost in cancers due to aberrant localization or downregulation of connexins, and connexins are therefore suggested to act as tumor suppressor genes in various tissues," scientists writing in the journal Epigenetics report.
"The aim of this study was to investigate the...
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Source: Cancer Weekly (2011-07-26)
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