Immunoglobulins
Data on Immunoglobulins Discussed by T. Maruyama and Colleagues
Published in Cancer Weekly, August 30th, 2011
2011 AUG 30 -- According to the authors of recent research from Yamanashi, Japan, "Although it was previously reported that lapatinib combined with Herceptin improved the progression-free survival rate compared with lapatinib alone for patients with Herceptin-refractory HER2-positive metastatic breast cancer, the mechanism is purported to be an antiproliferative effect relating to the synergism of these two agents. We evaluated how lapatinib interacts with Herceptin in HER2-positive breast cancer, with a particular focus on Herceptin-mediated antibody-dependent cellular cytotoxicity (ADCC)."
"In an in vitro assay, lapatinib induced HER2 expression at the...
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Source: Cancer Weekly (2011-08-30)
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