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Stem Cell Research

Research in the Area of Stem Cell Research Reported from National Hospital Organization

Published in Cancer Weekly, August 30th, 2011

2011 AUG 30 -- According to the authors of a study from Kyoto, Japan, "We aimed to demonstrate the existence of cancer stem cells in human pancreatic cancer, and to clarify that they are alpha-fetoprotein (AFP) producing cells. Six cell lines derived from human pancreatic cancers were examined, and AsPC-1 and PANC-1 were noted to express AFP."

"Single cell culture assays and xenotransplantation revealed that the AFP-producing cells had the capacity for self-renewal and differentiation, and that these cells were tumorigenic. Furthermore, they were resistant to anti-cancer agents. The ABCA12 transporter was expressed in the AFP-producing cells at a level more...

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