Published in Cancer Weekly, August 30th, 2011
"Using SILAC-proteomic analysis and molecular studies, we identified the AAA+ATPase, RuvBl2 as a transcriptional regulator of hTERT and established that this regulation is through cooperation with Ets-2. In colon cancer patients, nuclear expression of RuvBl2 associated with nuclear expression of hTERT, pEts2 and advanced nodal disease (P < 0.01, P = 0.05 and P =...
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