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Research from University of Uppsala Yields New Data on Cancer Research

Published in Cancer Weekly, September 13th, 2011

2011 SEP 13 -- A new study, "Effects of affinity on binding of HER2-targeting Affibody molecules: model experiments in breast cancer spheroids," is now available. According to the authors of recent research published in the International Journal of Oncology, "Binding of a targeting agent in tumor tissue is influenced by many factors such as molecular weight, charge and affinity of the targeting agent and vascularization of the tumor. In this study, we analyzed tumor cell binding of three HER2-specific and radiolabeled Affibody molecules with different affinities."

"The Affibody molecules had affinities in the range of 0.12-3.8 nM. Cellular binding...

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