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Breast Cancer

Researchers from Erasmus University Report Details of New Studies and Findings in the Area of Breast Cancer

Published in Cancer Weekly, September 20th, 2011

2011 SEP 20 -- Researchers detail in "Prevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families," new data in Breast Cancer. According to the authors of a study from Rotterdam, Netherlands, "Recently, a variant allele in the 3'UTR of the KRAS gene (rs61764370 T>G) was shown to be associated with an increased risk for developing non-small cell lung cancer, as well as ovarian cancer, and was most enriched in ovarian cancer patients from hereditary breast and ovarian cancer families. This functional variant has been shown to disrupt a let-7 miRNA binding site leading to increased expression of...

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