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Organic Chemistry

Research Conducted by P. Pailee and Co-Researchers Has Updated Our Knowledge about Organic Chemistry

Published in Cancer Weekly, September 27th, 2011

2011 SEP 27 -- "New protoberberine alkaloids, namely alangiumkaloids A (1) and B (2), 27-O-trans-caffeoylcylicodiscic acid (3), and beta-D-glucopyranos-1-yl N-methylpyrrole-2-carboxylate (5) together with myriceric acid B (4), isoalangiside (6), alangiside (7), 3-O-demethyl-2-O-methylalangiside (8), and demethylalangiside (9) have been isolated from Alangium salviifolium. The cancer chemopreventive properties and cytotoxic activities of the isolated compounds were evaluated," investigators in Bangkok, Thailand report.

"Compounds 3, 4, and 9 scavenged DPPH free radicals with IC50 values of 21.4, 21.8, and 24.0 mc M, respectively. Alangisides 7 and 9...

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