Breast Cancer

Reports Outline Breast Cancer Study Findings from R. Eeles and Colleagues

Published in Cancer Weekly, October 4th, 2011

2011 OCT 4 -- "Clonality of multicentric breast cancer has traditionally been difficult to assess. We aimed to assess this using analysis of TP53 status (expression and mutation status)," investigators in Cheshire, United Kingdom report.

"These results were then incorporated into an analysis of prognostic factors in multicentric tumours in a 10-year follow up study. Clonal status of multicentric breast cancer foci (n = 88 foci) was determined by immunohistochemical and molecular studies of TP53 in a total of 40 patients. Prognostic factors from these patients were also compared with 80 age- and stage-matched controls with unicentric breast cancer from the...

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Source: Cancer Weekly (2011-10-04)

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