Epithelial Cells
Study Results from Center for Biologics Evaluation and Research in the Area of Epithelial Cells Published
Published in Cancer Weekly, October 25th, 2011
2011 OCT 25 -- According to the authors of recent research from Rockville, Maryland, "The transcription factor, CCAAT enhancer binding protein-beta (C/EBP beta), is expressed as several distinct protein isoforms (LAP1, LAP2 and LIP) that have opposing actions in cellular proliferation and differentiation. Increases in the ratio of LIP/LAP are associated with aggressive, metastatic breast cancer; however, little is known regarding the molecular mechanisms that regulate LIP expression or the biological actions of an increase in the LIP/LAP ratio."
"Metastasis is highly dependent upon the suppression of anoikis and the role of C/EBP beta and LIP in this...
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Source: Cancer Weekly (2011-10-25)
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