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Biochemistry

Studies from University of Texas Medical Branch in the Area of Biochemistry Described

Published in Cancer Weekly, November 1st, 2011

2011 NOV 1 -- New research, "Checks and balances: interplay of RTKs and PTPs in cancer progression," is the subject of a report. According to the authors of recent research from Galveston, Texas, "In recent years, targeted therapies for receptor tyrosine kinases (RTKs) have shown initial promise in the clinical setting for the treatment of several tumors driven by these oncogenic signaling pathways. Unfortunately, clinical relapse due to acquired resistance to these molecular therapeutics is common."

"An improved understanding of how tumors bypass the inhibitory effects of RTK-targeted therapies has revealed a rich myriad of possible mechanisms for acquired...

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