Solid Cancer

Researchers from New York University Report Recent Findings in Solid Cancer

Published in Cancer Weekly, November 1st, 2011

2011 NOV 1 -- According to the authors of a study from New York City, New York, "Notch signaling is often considered a model hematopoietic proto-oncogene because of its role as the main trigger of T cell acute lymphoblastic leukemia (T-ALL)."

"Although its role in T-ALL is well characterized and further supported by a high frequency of activating NOTCH1 mutations in T-ALL patients, it still remains an open question whether the effects of Notch signaling are causative in other types of cancer, including solid tumors. Growing evidence supported by recent studies unexpectedly shows that Notch signaling can also have a potent tumor suppressor function in both...

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Source: Cancer Weekly (2011-11-01)

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