Findings from University of Pennsylvania Advance Knowledge in Cancer Biology

2011 NOV 1 -- New investigation results, "Novel surface targets and serum biomarkers from the ovarian cancer vasculature," are detailed in a study published in Cancer Biology & Therapy. According to the authors of recent research from Philadelphia, Pennsylvania, "The molecular phenotype of tumor vasculature is different from normal vasculature, offering new opportunities for diagnosis and therapy of cancer, but the identification of tumor-restricted targets remains a challenge. We investigated 13 tumor vascular markers (TVMs) from 50 candidates identified through expression profiling of ovarian cancer vascular cells and selected to be either transmembrane or secreted,...

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