Cancer Research

Study Data from University Health Network Update Understanding of Cancer Research

Published in Cancer Weekly, November 22nd, 2011

2011 NOV 22 -- According to the authors of a study from Toronto, Canada, "Patient selection for phase I trials (PIT) in oncology is challenging. A typical inclusion criterion for PIT is 'life expectancy > 3 months', however the 90 day mortality (90DM) and overall survival (OS) of patients with advanced solid malignancies are difficult to predict."

"We analyzed 233 patients who were enrolled in PIT at Princess Margaret Hospital. We assessed the relationship between 17 clinical characteristics and 90DM using univariate and multivariate logistic regression analyses to create a risk score (PMHI). We also applied the Royal Marsden Hospital risk score (RMI),...

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Source: Cancer Weekly (2011-11-22)

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