Diabetes

Research Data from B. Bartling and Colleagues Update Understanding of Diabetes

Published in Cancer Weekly, November 29th, 2011

2011 NOV 29 -- According to the authors of a study from Regensburg, Germany, "Both diabetes mellitus (DM) and non-small cell lung carcinoma (NSCLC) are age-related diseases and therefore occur simultaneously. DM and, in particular, diabetic nephropathy are associated with an increased modification of the extracellular tissue matrix with advanced glycation endproducts (AGEs)."

"As AGE-modified matrix impairs the invasive migration of lung carcinoma cells, our study aimed at the effect of DM on the NSCLC-related outcome. In a retrospective clinical study, we analyzed the time-dependent survival of NSCLC patients with DM compared to patients without DM, who...

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Source: Cancer Weekly (2011-11-29)

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