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Gynecology

New Findings from Hospital Clinic in the Area of Gynecology Published

Published in Cancer Weekly, December 6th, 2011

2011 DEC 6 -- "Human epididymis protein 4 (HE4), a precursor of human epididymis protein, has been proposed as a tumor marker for ovarian cancer. We evaluated HE4 in comparison with cancer antigen 125 (CA 125) in healthy individuals and in patients with benign and malignant diseases," investigators in Barcelona, Spain report.

"CA 125 and HE4 serum concentrations were determined in 101 healthy individuals, 535 patients with benign pathologies (292 with benign gynecologic diseases) and 423 patients with malignant diseases (127 with ovarian cancers). CA 125 and HE4 cutoffs were 35 kU/L and 140 pmol/L, respectively. HE4 and CA 125 results were abnormal in 1.1%...

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