Sanford-Burnham Medical Research Institute

Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment

Published in Cancer Weekly, December 6th, 2011

2011 DEC 6 -- "We can cure terminal stage mice with very large tumors without any side effects simply by giving them this drug coupled with IF7," said Dr. Fukuda, professor in Sanford-Burnham's National Cancer Institute (NCI)-designated Cancer Center and corresponding author of the study.

Carbohydrates coat the surface of every cell in the body. They-and the proteins that bind them-play important roles in many cellular processes, including tumor formation and cancer metastasis. However, unlike genes or proteins, carbohydrates are difficult to synthesize in the lab. To get around that hurdle, Dr. Fukuda and her team tested a collection of short proteins...

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Source: Cancer Weekly (2011-12-06)

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