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Lewis Lung Cancer

Research from Medical University of South Carolina in Lewis Lung Cancer Provides New Insights

Published in Cancer Weekly, December 27th, 2011

2011 DEC 27 -- A new study, "NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells," is now available. According to the authors of recent research from Charleston, South Carolina, "Tumor-induced immune suppression involves the accumulation of suppressive infiltrates in the tumor microenvironment such as regulatory T-cells (Tregs). Previous studies demonstrated that NK-dependant increases in CCL22 secretion selectively recruit Tregs toward murine lungs bearing Lewis Lung Carcinoma (LLC)."

"To extend the in vitro studies, the present studies utilized in vivo...

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