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Vascular Endothelial Growth Factor

New Vascular Endothelial Growth Factor Research from Beth Israel Deaconess Medical Center Outlined

Published in Cancer Weekly, January 24th, 2012

2012 JAN 24 -- Investigators discuss in "Tumor-surrogate blood vessel subtypes exhibit differential susceptibility to anti-VEGF therapy" new findings in Vascular Endothelial Growth Factor. "Antivascular therapy directed against VEGF or its receptors (VEGFR) has been successful when administered at early stages of tumor vessel growth but is less effective when administered later. Tumor blood vessels are heterogeneous, so vessel subpopulations may differ in their requirements for tumor cell-secreted VEGF and in their susceptibility to anti-VEGF/VEGFR therapy," investigators in Boston, Massachusetts report.

"Human cancers contain several distinct blood vessel...

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