Lung Cancer
Scientists at Third Military Medical University Detail Research in Lung Cancer
Published in Cancer Weekly, January 24th, 2012
2012 JAN 24 -- A new study, "Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells," is now available. According to the authors of a study from Chongqing, People's Republic of China, "Non-metastatic protein-23 homolog-1 (Nm23-H1) is a multifunctional protein with DNase and histidine protein kinase activities. Human apurinic endonuclease-1 (APE1) is the AP endonuclease DNA base excision repair (BER) enzyme involved in several important cellular functions."
"Since the relationship between Nm23-H1 and APE1 proteins is unclear, we evaluated their interaction at...
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Source: Cancer Weekly (2012-01-24)
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