Breast Cancer

Research from University of Naples Federico II Provides New Insights into Breast Cancer

Published in Cancer Weekly, February 21st, 2012

2012 FEB 21 -- "The SRC family of ER co-regulators are frequently overexpressed in breast cancer. Overexpression of AIB1 appears to be linked to hormone resistance in HER2 positive breast cancer," scientists in Naples, Italy report.

"However, the role of these co-regulators in ER negative disease is poorly understood. SRC1, SRC2 and AIB1 expression was determined by immunohistochemical analysis of tissue microarrays constructed from tumours within the Edinburgh Breast Conservation Series (BCS). The BCS represents a fully documented consecutive cohort of 1,812 patients treated by breast conservation surgery in a single institution. Our results demonstrate...

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Source: Cancer Weekly (2012-02-21)

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