Colorectal Research

Studies from Sher-I-Kashmir Institute of Medical Sciences Add New Findings in the Area of Colorectal Research

Published in Cancer Weekly, February 21st, 2012

2012 FEB 21 -- Research findings, "Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population," are discussed in a new report. According to the authors of a study from Srinagar, India, "Cytochrome P450 2E1 (CYP2E1) is a key enzyme involved in the metabolic activation of procarcinogens such as N-nitrosoamines and low-molecular-weight organic compounds. The main aim of this study was to determine whether CYP450 2E1 polymorphisms are associated with the risk of colorectal cancer (CRC)."

"We investigated the genotype distribution of the CYP2E1 gene RsaI and a 96-base pair (bp) insertion in 86 CRC cases in comparison with 160...

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Source: Cancer Weekly (2012-02-21)

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