Physiology

Reports from University of Michigan Highlight Recent Research in Physiology

Published in Cancer Weekly, February 28th, 2012

2012 FEB 28 -- "The Hedgehog pathway is one of the most common signal transduction pathways used by mammalian cells. Most studies have focused on its role during development, primarily of the nervous system, skin, bone and pancreas," scientists writing in the Journal of Physiology-London report.

"Due to the activation of this pathway during proliferation and neoplastic transformation, more recent studies have examined its role in adult tissues. Significant levels of sonic hedgehog are expressed in the gastric mucosa, which has served to direct analysis of its role during organogenesis, gastric acid secretion and neoplastic transformation," wrote J.L....

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Source: Cancer Weekly (2012-02-28)

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