Breast Cancer
Data from University of California Advance Knowledge in Breast Cancer
Published in Cancer Weekly, March 6th, 2012
2012 MAR 6 -- "While genetic mutation is a hallmark of cancer, many cancers also acquire epigenetic alterations during tumorigenesis including aberrant DNA hypermethylation of tumor suppressors, as well as changes in chromatin modifications as caused by genetic mutations of the chromatin-modifying machinery. However, the extent of epigenetic alterations in cancer cells has not been fully characterized," scientists writing in the journal Genome Research report.
"Here, we describe complete methylome maps at single nucleotide resolution of a low-passage breast cancer cell line and primary human mammary epithelial cells. We find widespread DNA...
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Source: Cancer Weekly (2012-03-06)
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