T-Lymphocyte Antigens
Researchers from University Children's Hospital Report Recent Findings in T-Lymphocyte Antigens
Published in Cancer Weekly, March 6th, 2012
2012 MAR 6 -- Data detailed in "Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapy" have been presented. According to the authors of a study from Wurzburg, Germany, "T cell-mediated immunotherapy against malignancies has been shown to be effective for certain types of cancer. However, ex vivo expansion of tumor-reactive T cells has been hindered by the low precursor frequency of such cells, often requiring multiple rounds of stimulation, resulting in full differentiation, loss of homing receptors and potential exhaustion of the expanded T cells."
"Here, we show that when using highly purified naive CD8+ T cells, a single...
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Source: Cancer Weekly (2012-03-06)
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