Cancer Research
New Cancer Research Study Findings Recently Were Reported by Researchers at University of Michigan
Published in Cancer Weekly, March 20th, 2012
2012 MAR 20 -- A report, "Tumorigenic Cells Are Common in Mouse MPNSTs but Their Frequency Depends upon Tumor Genotype and Assay Conditions," is newly published data in Cancer Cell. According to the authors of a study from Ann Arbor, Michigan, "Tumor-initiating cells have been suggested to be rare in many cancers. We tested this in mouse malignant peripheral nerve sheath tumors (MPNSTs) and found that 18% of primary and 49% of passaged MPNST cells from Nf1(±); Ink4a/Arf(-/-) mice formed tumors upon transplantation, whereas only 1.8% to 2.6% of MPNST cells from Nf1(±); p53(±) mice did."
"MPNST cells of both genotypes require...
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Source: Cancer Weekly (2012-03-20)
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