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Colon Cancer

Researchers at French National Institute of Health and Medical Research (INSERM) Have Published New Data on Colon Cancer

Published in Cancer Weekly, March 20th, 2012

2012 MAR 20 -- New investigation results, "MiRNA Genes Constitute New Targets for Microsatellite Instability in Colorectal Cancer," are detailed in a study published in Plos One. "Mismatch repair-deficient colorectal cancers (CRC) display widespread instability at DNA microsatellite sequences (MSI). Although MSI has been reported to commonly occur at coding repeats, leading to alterations in the function of a number of genes encoding cancer-related proteins, nothing is known about the putative impact of this process on non-coding microRNAs," scientists in Paris, France report.

"In miRbase V15, we identified very few human microRNA genes with mono-or...

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