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Colon Cancer

Scientists at University of Melbourne Target Colon Cancer

Published in Cancer Weekly, March 20th, 2012

2012 MAR 20 -- Research findings, "Pro-GRP-Derived Peptides Are Expressed in Colorectal Cancer Cells and Tumors and Are Biologically Active in Vivo," are discussed in a new report. According to the authors of recent research from Heidelberg, Australia, "Amidated gastrin-releasing peptide (GRP) is the prototypical autocrine growth factor. Nonamidated peptides derived from the C terminus of pro-GRP are also biologically active in colorectal cancer (CRC) cell lines in vitro, via a receptor distinct from the GRP receptor."

"The aims of this study were to measure the amounts of pro-GRP-derived peptides in human CRC cell lines and tumors, characterize the...

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