Colon Cancer

Recent Studies from University of Tunis Add New Data to Colon Cancer

Published in Cancer Weekly, April 3rd, 2012

2012 APR 3 -- According to the authors of recent research from Tunis, Tunisia, "The K-ras proto-oncogene encodes a protein (p21-ras) belonging to the family of GTP/GDP-binding proteins with GTPase activity. The activation of ras family genes plays an important role in colorectal tumorigenesis."

"Frequency of K-ras mutations and overexpression of the protein in colorectal cancer (CRC) vary between 14% and 50% and between 29% and 76%, respectively. We investigated the clinicopathologic characteristics of patients with CRC and their relationship with point mutations of K-ras oncogene codons 12/13 and ras p21 expression. K-ras codons 12 and 13 point mutations...

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Source: Cancer Weekly (2012-04-03)

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