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Lung Cancer

Researchers from Chinese People's Liberation Army General Hospital Report Recent Findings in Lung Cancer

Published in Cancer Weekly, April 10th, 2012

2012 APR 10 -- Research findings, "AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer," are discussed in a new report. According to the authors of recent research published in the journal Tumor Biology, "The purpose of this study is to determine the epigenetic changes and function of High in Normal-1 (HIN-1) in non-small cell lung cancer (NSCLC). HIN-1 expression was examined by semiquantitative RT-PCR before and after 5-aza-2'-deoxycytidine (5-aza) treatment in NSCLC cell lines."

"Promoter methylation status of HIN-1 was tested by methylation-specific PCR (MSP). Effect of forced expression of HIN-1 on different key...

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