Nasopharyngeal Carcinoma
Study Results from University Putra Malaysia Provide New Insights into Nasopharyngeal Carcinoma
Published in Cancer Weekly, April 17th, 2012
2012 APR 17 -- A report, "Activation of phosphatidylinositol 3-kinase/Akt signaling by EGF downregulates membranous E-cadherin and ß-catenin and enhances invasion in nasopharyngeal carcinoma cells," is newly published data in Cancer Letters. "Dysregulation of E-cadherin and ß-catenin function in cell-cell adhesion is common in nasopharyngeal carcinoma (NPC) and correlates with metastatic disease. In this study, we examined the role of EGF-activated phosphatidylinositol 3-kinase (PI3K)-Akt signaling in E-cadherin and ß-catenin regulation," scientists in Selangor, Malaysia report.
"We found that reduced membranous E-cadherin and...
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Source: Cancer Weekly (2012-04-17)
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