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Cancer Research

Data on Cancer Research Reported by Researchers at University Hospital

Published in Cancer Weekly, April 24th, 2012

2012 APR 24 -- According to the authors of recent research published in the journal Strahlentherapie Und Onkologie, "High levels of hypoxia inducible factor (HIF)-1 alpha in tumors are reported to be associated with tumor progression and resistance to therapy. To examine the impact of HIF-1 alpha on radioresistance under normoxia, the sensitivity towards irradiation was measured in human tumor cell lines that differ significantly in their basal HIF-1 alpha levels."

"HIF-1 alpha levels were quantified in lysates of H1339, EPLC-272H, A549, SAS, XF354, FaDu, BHY, and CX- tumor cell lines by ELISA. Protein levels of HIF-1 alpha, HIF-2 alpha, carbonic...

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