Colon Cancer

Study Results from Masaryk University Provide New Insights into Colon Cancer

Published in Cancer Weekly, April 24th, 2012

2012 APR 24 -- "The development of colorectal cancer (CRC) is characterized by multiple genetic alterations. Transcribed ultraconserved regions (T-UCRs) are a subset of 481 sequences longer than 200 bp, which are absolutely conserved between orthologous regions of human, rat and mouse genomes, and are actively transcribed," researchers in Brno, Czech Republic report.

"It has recently been proven in cancer systems that differentially expressed T-UCRs could alter the functional characteristics of malignant cells. Genome-wide profiling revealed that T-UCRs have distinct signatures in human leukemia and carcinoma. In our study, we examined the expression levels...

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Source: Cancer Weekly (2012-04-24)

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