Cancer Research

Researchers from University of New South Wales Report Details of New Studies and Findings in the Area of Cancer Research

Published in Cancer Weekly, April 24th, 2012

2012 APR 24 -- In this recent article published in the journal Cancer Letters, scientists in Sydney, Australia conducted a study "To identify epigenetic-based biomarkers for diagnosis of ovarian cancer we performed MeDIP-Chip in A2780 and CaOV3 ovarian cancer cell lines."

"Validation by Sequenom massARRAY methylation analysis confirmed a panel of six gene promoters (ARMCX1, ICAM4, LOC134466, PEG3, PYCARD & SGNE1) where hypermethylation discriminated 27 serous ovarian cancer clinical samples versus 12 normal ovarian surface epithelial cells (OSE) (ROC of 0.98). Notably, CpG sites across the transcription start site of a potential long-intergenic...

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Source: Cancer Weekly (2012-04-24)

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