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Cardiovascular Business Week

Susan Hasty, Publisher

Table of Contents . . . March 30th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cardiovascular Business Week | Other Publications

Wolfson Inst. of Preventive Medicine - High blood pressure is a poor predictor of heart disease

WellSpring Pharmaceutical Corporation - Dyrenium diuretic drug to be marketed to physicians online

Vanderbilt University Medical Center - Angiotensin II causes oxidative stress in hypertension patients

University of Washington - PET can help determine regional sympathetic function during heart disease

University of Warwick, England - Rural South Africa faces stroke crisis similar to affluent Western countries

University of Vienna - Polymorphism in gene promoter linked to increased bilirubin and HDL levels

University of Verona - Lipid profiles are significantly related to bone mass in women and men

University of Pennsylvania - Study links lung disease with heart problems

University of Pennsylvania - Inhibition of myocardial cytochrome C oxidase involved in sepsis

University of Pennsylvania - Effects of tPA and PAI-1 on blood vessel tone described

University of Nottingham - Prostaglandin E1 enhances inhibition of platelet aggregation

University of Nebraska - A large-sample QTL study in mice examined body composition

University of Milan - High heart rate reduces arterial distensibility

University of Michigan - Implanted defibrillators not covered for patients who could benefit

University of Manchester - ACE gene polymorphism linked to damage in Alzheimer disease

University of Lyon - Resuscitative transverse thoracotomy helps control circulatory arrest

University of Leipzig - Daily aerobic activity treats chest pain, at half the cost of stenting

University of Iowa - America's teens are growing up and out

University of Illinois - Antithrombins suppress angiogenesis by down-regulating perlecan

University of Illinois - Angiotensin II attenuates caspase-3 activation in cortical neurons

University of Florida - World Trade Center attack linked to rise in irregular heartbeats in Florida patients

University of Florida - Angiotensin II increases tyrosine hydroxylase production in rat adrenal medulla

University of Edinburgh - New treatment may help patients with kidney failure

University of Cincinnati - New drug helps smokers quit while limiting post-cessation weight gain

University of California - Donation of patents may accelerate new treatment for global health problem

University of Birmingham - Tedisamil has multiple cardioprotective effects

Univ. of Texas, Houston - Problems controlling anger lead to weight gain for teens

University of Alberta - Drug appears safe for some men with congestive heart failure

Univ. of Texas SW Medical Center - Rate of LV hypertrophy progression to heart failure evaluated

Univ. of Texas Health Science Cntr., San Antonio - Antisense knockdown in zebrafish models mammalian prothrombin deficiency

Univ. of Michigan Health System - National medical privacy law makes health research harder, more expensive

Univ. of Michigan Health System - Following care guidelines reduces risk of death within 1 year of heart attack

Univ. of California, San Francisco - Multicenter trial compares three medications in patients with heart failure

Univ. of California, Davis - Antioxidant therapy helps manage diabetic cardiovascular disease

U.S. National Institutes of Health - African Americans unaware of high kidney disease risk

U.S. Centers for Disease Control & Prevention - Poor diet, physical inactivity may soon overtake tobacco as leading cause of death

U.S. Centers for Disease Control & Prevention - Folic acid fortification may have lowered stroke deaths

Turku University - Myocardial perfusion not linked to peripheral endothelial function

Tufts University - GATA-4 transcription factor regulates cardiac myocyte apoptosis

Tulane University - High blood pressure in China looks like U.S. 25 years ago

TriZetto Group, Inc. - HMO upgrades management software to offer members broader products, services

Thoratec Corporation - Heartmate XVE shipping with new inflow valve

Thomas Jefferson University - Metabolic "footprint" may be new measure of heart risk in obese kids

Tel-Aviv Sourasky Medical Center - Leukocyte counts may have prognostic value in acute CVD

Thermogenesis Corp. - Trial completed on CryoSeal system in Japan

Synta Pharmaceuticals Corp. - Pharmaceuticals company announces new scientific advisory board members

Stem-Cell Research - U.S. lawmakers want to ease stem cell research restrictions

Stanford University - Study looks at cost of high blood pressure therapy

Sono-Tek Corporation - AccuMist Stent Coating System sales announced

Skejby University Hospital - Cardiac troponin I mutation linked to idiopathic dilated cardiomyopathy

Shiga University of Medical Science - AT1 receptors linked to insulin resistance-induced vascular dysfunction

San Raffaele H. Science Institute - Chromogranin A offers vessels protection against TNF-alpha-induced leakage

Seattle Institute for Cardiac Research - Implanted defibrillator reduces heart failure deaths

Ruhr University of Bochum - AT2 -receptor antagonists block Ang II effects on atrial noradrenaline release

Rubicon Medical Corp. - Martin Leon to lead studies of Rubicon Filter

Research Institute of Cardiology, Minsk - Interstitial purine metabolites elevated during post-MI LV remodeling

Royal Netherlands Academy of Arts & Sciences - MCIP1 overexpression preserves post-infarction cardiac function

Regulatory Issues - 'Certificate of Need' laws lead to improved patient outcomes for some procedures

Point Biomedical Corp. - CARDIOsphere evaluated for diagnosing coronary artery disease

Personnel - Jacque J. Sokolov, MD, named to MedCath board

Personnel - Northwestern Memorial names Patrick McCarthy as chief of cardiac surgery

Obesity - Obesity could top smoking as No. 1 cause of preventable death in the U.S.

Nutrition 21, Inc. - Research: Lower chromium levels linked to increased risk of disease

Northwestern University - Questions raised about do-not-resuscitate orders and shorter hospital stays

New Jersey Medical School - The symptoms of spinal cord infarction warrant caution in pregnant women

Neoprobe Corp. - FDA meeting to discuss RIGScan CR49 development

Nebraska Medical Center - Microalbuminuria is marker of heart and kidney disease risk in diabetes

National Yang Ming University - Endothelial catalase overexpression attenuates oxidant-mediated injury

Nagoya University - Peptide array used to identify Ang II inhibitory peptide

Mount Sinai Hospital - Studies reinforce potential benefits of new stroke-prevention drug

Morehouse School of Medicine - Obesity leads to high blood pressure in the young

MicroMed Technology, Inc. - New children's heart pump may save lives

Millar Instruments, Inc. - New pressure-volume systems launched

MicroMed Technology Inc. - Miniaturized heart pump for children approved by FDA

Metabolex, Inc. - Phase II trial of insulin sensitizer MBX-102 begins

Medtronic, Inc. - Mosaic and Freestyle porcine-tissue heart valves reintroduced in Japan

Medical University of Lodz - Atorvastatin and fluvastatin have plasma antioxidative activity

McMaster University - Baseline data from heart protection trial reveal dramatic shift in treatment

Lyon-South Hospital Center - Propylthiouracil is preferred therapy for pregnant women with thyroid disease

Leicester Royal Infirmary - Urinary N-BNP suitable for heart failure diagnosis

Leiden University - Post-revascularization contractile recovery in LV dysfunction patients evaluated

Johnson & Johnson - Drug-coated stents aid heart procedure

Johns Hopkins University - CAC deposits linked to elevated LV mass in African-Americans

IRCCS, Tradate - T wave alternans predicts mortality in congestive heart failure patients

INSERM U533, Nantes - Mechanisms downstream of P2Y12 ADP-receptor described

Information Technology - New Jersey center joins ranks of ProSolv CardioVascular users

Howard University Hospital. - Lipoproteina levels respond to life-style changes in obese adults

Harvard University - Hypertension-induced cardiac remodeling reviewed

Harvard University - Endothelial progenitor cells are detected in infantile hemangioma

GTC Biotherapeutics - Company presents ATryn safety and efficacy data

Genentech, Inc. - Early treatment confirmed as key to stroke recovery

Eyetech Pharmaceuticals, Inc. - Macugen data presented at Aspen Retinal Detachment Society meeting

GE Healthcare - Panel discusses new "before-onset care" paradigm

Emory University - Matrix metalloproteinase-9 is needed for revascularization after ischemic injury

Emory University - Emory researchers find race and gender gaps in treatment of heart attack

Edwards Lifesciences Corporation - Heart valve maker to partner in deal for commercialization of laser technology

Duke University Medical Cntr. - State-required CME: No effect on heart attack care, boosts use of branded drugs

Duke University Medical Cntr. - Hospitals following heart attack guidelines have better outcomes

Duke University Medical Center - Beta blockers usage low despite insurance

Duke University - State-required continuing medical education does not affect heart attack care

Duke University - Progenitor cells predict heart disease severity

Duke University - Community hospitals do not transfer high-risk heart patients for aggressive therapy

Diomed Holdings, Inc. - Joseph Harris named to board of EndoVenous laser treatment maker

Creighton University, Omaha - Safety, efficacy of endovascular intracoronary brachytherapy reviewed

CTSNet, Inc. - Grant to support education and innovation in cardiothoracic surgery

Correction - Nebraska aims to protect children from methamphetamine labs

Complementary & Alternative Medicine - U.S. orders halt to sales of the supplement andro

Columbia University - Biventricular pacing may induce electrical remodeling

Collaborations - QMed, Inc. to provide diabetes and coronary disease management to WHA

Cochin Hospital, Paris - Biomarkers of acute coronary artery disease reviewed

Cleveland Clinic Foundation - Study: Cholesterol lowering with atorvastatin halts progression of heart disease

Case Western Reserve University - New technique tracks irregular heartbeats

Childbirth - Temperature at birth linked to health later in life

CardioTech International, Inc. - Device company names new board member

Bristol-Myers Squibb - Study: Lower cholesterol helps save lives

Bristol-Myers Squibb - Agreements inked to develop novel molecular imaging agents

Boston University - Diet, avoidance of smoking are primary ways for women to prevent heart disease

Bristol Myers Squibb Co. - Selective inhibitors of mitochondrial F1 F0 ATP hydrolase synthesized

Boston University - Dairy, moderate fat, carbohydrate intakes reduce obesity in young teens

Biosite Incorporated - Cardiovascular discovery collaboration signed with DMI BioSciences

BioSensus - At-home device would check blood thinning

Baylor College of Medicine - GP Ialpha genotype affects CHD risk

AuntMinnie.com - Cardiac imaging digital community launched

AstraZeneca - Group seeks ban of anticholesterol drug

AstraZeneca - Apolipoprotein risk factors for CVD reviewed

Angiotech Pharmaceuticals, Inc. - FDA approval granted for Taxus Express2 paclitaxel-eluting stent system

American Heart Association - AHA responds to findings from Women's Health Initiative

Akdeniz University, Antalya - Transplantation of tissues enhances quality of life in many patients

Ajou University - Elevated LVEDP may induce myocardial cytokine release

Adolescent Health - Six states plan anti-huffing program for teens that get high on inhalants

Abiomed, Inc. - Twelfth implant of AbioCor replacement heart reported

Abbott Laboratories - Agreement signed for Chagas disease blood screening technology

NanoSignal Corp. - Company opens new sales office in India for SLICES and distribution of shares

Vasogen Inc. - Therapeutics company announces closing of $57.7M common share offering

- IBD is a risk factor for thrombosis

Evalve, Inc. - Clip device accomplishes endovascular, nonsurgical repair of faulty heart valve

Guilford Pharmaceuticals, Inc. - Analysis from TACTICS-TIMI 18 trial published

Cardiac Science, Inc. - Defibrillator maker reports revenue increase of 24%

Alteon, Inc. - Alagebrium chloride approved as generic name for ALT-711

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